Genome-wide association study

In genetic epidemiology Genetic epidemiology is the study of the role of genetic factors in determining health and disease in families and in populations, and the interplay of such genetic factors with environmental factors. In slightly more formal language, genetic epidemiology was defined by Morton as "a science which deals with the etiology, distribution, and, a genome-wide association study In genetic epidemiology, a genome-wide association study - also known as whole genome association study (WGA study) - is an examination of genetic variation across a given genome, designed to identify genetic associations with observable traits. In human studies, this might include traits such as blood pressure or weight, or why some people get a (GWA study, or GWAS) is an examination of genetic variation across a given genome In classical genetics, the genome of a diploid organism including eukarya refers to a full set of chromosomes or genes in a gamete; thereby, a regular somatic cell contains two full sets of genomes. In haploid organisms, including bacteria, archaea, viruses, and mitochondria, a cell contains only a single set of the genome, usually in a single, designed to identify genetic associations with observable traits. In human studies, this might include traits such as blood pressure or weight, or why some people get a disease or condition.[21]

A 2007 study by Bauchet et al. found that Ashkenazi Jews were most closely clustered with Arabic North African populations, and in the European structure analysis they share similarities only with Greeks and Southern Italians, reflecting their East Mediterranean origins.[22]

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